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Jerome I Rotter Selected Research

Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)

6/2023Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response.
1/2022Circulating Metabolome and White Matter Hyperintensities in Women and Men.
1/2022Determinants of Incident Atherosclerotic Cardiovascular Disease Events Among Those With Absent Coronary Artery Calcium: Multi-Ethnic Study of Atherosclerosis.
1/2021The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.
8/2020Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines.
1/2020Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study.
10/2018LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins.
11/2017Association of Mitochondrial DNA Copy Number With Cardiovascular Disease.
8/2017PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites.
1/2017Pharmacometabolomic signature links simvastatin therapy and insulin resistance.
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Jerome I Rotter Research Topics

Disease

73Insulin Resistance
05/2024 - 05/2002
67Atherosclerosis
05/2024 - 08/2003
58Cardiovascular Diseases (Cardiovascular Disease)
05/2024 - 06/2004
56Type 2 Diabetes Mellitus (MODY)
05/2024 - 10/2002
29Obesity
05/2024 - 05/2002
26Hypertension (High Blood Pressure)
04/2024 - 02/2002
25Inflammation (Inflammations)
12/2024 - 01/2008
24Coronary Artery Disease (Coronary Atherosclerosis)
05/2024 - 07/2003
20Coronary Disease (Coronary Heart Disease)
01/2024 - 04/2003
19Crohn Disease (Crohn's Disease)
11/2018 - 02/2004
12Genetic Risk Score
04/2024 - 02/2014
11Stroke (Strokes)
01/2022 - 09/2013
10Diabetic Retinopathy (Retinopathy, Diabetic)
01/2023 - 02/2002
10Ulcerative Colitis
06/2012 - 05/2007
9Myocardial Infarction
05/2024 - 01/2012
9Chronic Obstructive Pulmonary Disease (COPD)
02/2024 - 04/2014
9Alzheimer Disease (Alzheimer's Disease)
11/2023 - 01/2017
8Prediabetic State (Prediabetes)
05/2024 - 07/2010
8Neoplasms (Cancer)
05/2024 - 03/2011
7Genetic Predisposition to Disease (Genetic Predisposition)
01/2024 - 10/2009
7Non-alcoholic Fatty Liver Disease
10/2023 - 11/2010
7Atrial Fibrillation
12/2021 - 02/2010
7Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2017 - 04/2004
6Keratoconus
01/2021 - 10/2011
5Apnea
12/2022 - 01/2019
5Heart Failure
01/2022 - 02/2013
5Macular Degeneration (Age-Related Maculopathy)
12/2017 - 01/2013
5Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2016 - 09/2002
4Body Weight (Weight, Body)
03/2024 - 01/2016
4Metabolic Diseases (Metabolic Disease)
01/2023 - 07/2007
4Abdominal Obesity
04/2012 - 07/2007
3Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
01/2024 - 01/2019
3Cognitive Dysfunction
11/2023 - 01/2017
3Hyperlipidemias (Hyperlipidemia)
10/2023 - 05/2013
3Aortic Valve Stenosis (Aortic Stenosis)
03/2023 - 11/2014
3Infertility (Sterility)
01/2023 - 01/2019
3Obstructive Sleep Apnea
12/2022 - 06/2020
3Dyslipidemias (Dyslipidemia)
10/2022 - 10/2011
3Emphysema
01/2022 - 04/2014
3Hypoxia (Hypoxemia)
01/2022 - 11/2017
3Breast Neoplasms (Breast Cancer)
12/2021 - 07/2012
3Sleep Apnea Syndromes (Sleep Apnea)
11/2021 - 11/2019

Drug/Important Bio-Agent (IBA)

61Glucose (Dextrose)FDA LinkGeneric
12/2023 - 05/2002
51Insulin (Novolin)FDA Link
12/2023 - 05/2002
41LipidsIBA
11/2023 - 05/2002
36Proteins (Proteins, Gene)FDA Link
02/2024 - 02/2007
28Biomarkers (Surrogate Marker)IBA
12/2024 - 09/2002
28LDL CholesterolIBA
01/2024 - 03/2006
18oxidized low density lipoproteinIBA
01/2024 - 03/2006
18Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
06/2023 - 03/2008
17Triglycerides (Triacylglycerol)IBA
01/2023 - 03/2006
16HDL CholesterolIBA
01/2022 - 04/2004
14CholesterolIBA
05/2024 - 03/2010
14CalciumIBA
03/2023 - 12/2010
13DNA (Deoxyribonucleic Acid)IBA
01/2023 - 08/2004
13AdiponectinIBA
08/2020 - 06/2006
10C-Reactive ProteinIBA
12/2024 - 07/2007
8Mitochondrial DNA (mtDNA)IBA
10/2023 - 11/2017
7P-2 (P 2)IBA
05/2024 - 02/2014
7Apolipoproteins E (ApoE)IBA
10/2023 - 01/2013
7AntigensIBA
08/2010 - 02/2002
6NucleotidesIBA
05/2024 - 09/2002
6Retinaldehyde (Retinal)IBA
01/2024 - 10/2010
6Hemoglobins (Hemoglobin)IBA
12/2023 - 04/2015
6AntibodiesIBA
01/2019 - 02/2004
6Lipoprotein Lipase (Diacylglycerol Lipase)IBA
01/2018 - 07/2003
6Genetic Markers (Genetic Marker)IBA
12/2017 - 06/2004
5EnzymesIBA
11/2023 - 01/2019
5ProteomeIBA
10/2023 - 01/2022
5ApolipoproteinsIBA
10/2023 - 05/2002
5Fibrinogen (Factor I)FDA Link
06/2023 - 09/2013
5Fatty Acids (Saturated Fatty Acids)IBA
01/2023 - 03/2014
5Vitamin DFDA LinkGeneric
01/2022 - 08/2017
5LDL Lipoproteins (beta Lipoproteins)IBA
01/2021 - 10/2013
5Lipoproteins (Lipoprotein)IBA
12/2017 - 08/2009
5Blood Glucose (Blood Sugar)IBA
04/2015 - 05/2008
4Polymethyl Methacrylate (Sol)IBA
04/2024 - 01/2017
4Transcription Factors (Transcription Factor)IBA
01/2024 - 01/2008
4RNA (Ribonucleic Acid)IBA
08/2023 - 11/2021
4Lipoprotein(a)IBA
01/2023 - 05/2012
4Antihypertensive Agents (Antihypertensives)IBA
01/2023 - 11/2010
4Hormones (Hormone)IBA
01/2022 - 01/2012
4Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
01/2022 - 02/2002
4Insulin-Like Growth Factor I (IGF-1)IBA
12/2021 - 03/2011
4Oxyhemoglobins (Oxyhemoglobin)IBA
01/2021 - 01/2019
4HDL LipoproteinsIBA
01/2018 - 05/2012
4Simvastatin (Zocor)FDA LinkGeneric
01/2017 - 03/2006
4AdipokinesIBA
12/2013 - 01/2013
4Interleukin-23 (Interleukin 23)IBA
09/2012 - 12/2006
3ChemokinesIBA
05/2024 - 11/2015
3Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
01/2023 - 01/2018
3Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
01/2023 - 07/2015
3Oxygen (Dioxygen)IBA
01/2023 - 11/2017
3CarbohydratesIBA
01/2023 - 01/2019
3Alanine Transaminase (SGPT)IBA
01/2022 - 01/2021
3Insulin-Like PeptidesIBA
12/2021 - 01/2016
3Amyloid (Amyloid Fibrils)IBA
01/2021 - 01/2019

Therapy/Procedure

20Therapeutics
02/2024 - 07/2004
19Precision Medicine
05/2024 - 10/2020
4Glycemic Control
01/2021 - 09/2017